Function and Biology Details
Reaction catalysed:
Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Low-density lipoprotein (LDL) receptor class A repeat
- Serine proteases, trypsin domain
- LDL receptor-like superfamily
- Peptidase S1A, chymotrypsin family
- SRCR domain
- SRCR-like domain superfamily
- Serine proteases, trypsin family, serine active site
- Serine proteases, trypsin family, histidine active site
7 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Complement factor I (preferred)
PDBe Complex ID:
PDB-CPX-138563 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule: