› 2y4t

X-ray diffraction
3Å resolution

Crystal structure of the human co-chaperone P58(IPK)

Released:
DOI: 10.2210/pdb2y4t/pdb
PDB entry 2y4t coloured by chain, front view.
PDB entry 2y4t coloured by chain, side view.
PDB entry 2y4t coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the human co-chaperone P58(IPK).
Svärd M, Biterova EI, Bourhis JM, Guy JE
PLoS One 6 e22337 (2011)
PMID: 21799829

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171604 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DnaJ homolog subfamily C member 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 450 amino acids
Theoretical weight: 51.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13217 (Residues: 35-461; Coverage: 90%)
Gene names: DNAJC3, P58IPK, PRKRI
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: R32
Unit cell:
a: 212.25Å b: 212.25Å c: 283.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.246 0.243 0.291
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Molecular chaperone functions in protein folding and proteostasis.
Kim et al. (2013)
6 more

4 mentions without citation

The crystal structure of the human co-chaperone P58(IPK).
Svärd et al. (2011)
3 more