› 2yan

X-ray diffraction
1.9Å resolution

Crystal structure of the second glutaredoxin domain of human TXNL2

Released:
DOI: 10.2210/pdb2yan/pdb
PDB entry 2yan coloured by chain, front view.
PDB entry 2yan coloured by chain, side view.
PDB entry 2yan coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Johansson C, Cocking R, Muniz JRC, Krojer T, Allerston C, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutaredoxin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 11.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O76003 (Residues: 232-334; Coverage: 31%)
Gene names: GLRX3, HUSSY-22, PICOT, TXNL2
Sequence domains: Glutaredoxin
Structure domains: Glutaredoxin

Ligands and Environments

5 bound ligands:
Ligand EDO 7 x EDO
Ligand FE 1 x FE
Ligand SO4 1 x SO4
Ligand CL 1 x CL
Ligand GSH 2 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P3221
Unit cell:
a: 118.317Å b: 118.317Å c: 58.84Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.185 0.212
Expression system: Escherichia coli BL21(DE3)

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