2ygs

X-ray diffraction
1.6Å resolution

CARD DOMAIN FROM APAF-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-127061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptotic protease-activating factor 1 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O14727 (Residues: 1-92; Coverage: 7%)
Gene names: APAF1, KIAA0413
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 56.7Å b: 36Å c: 47.9Å
α: 90° β: 118.2° γ: 90°
R-values:
R R work R free
0.198 0.198 0.236
Expression system: Escherichia coli BL21(DE3)