› 2yhx

X-ray diffraction
2.1Å resolution

SEQUENCING A PROTEIN BY X-RAY CRYSTALLOGRAPHY. II. REFINEMENT OF YEAST HEXOKINASE B CO-ORDINATES AND SEQUENCE AT 2.1 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb2yhx/pdb
PDB entry 2yhx coloured by chain, front view.
PDB entry 2yhx coloured by chain, side view.
PDB entry 2yhx coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Sequencing a protein by x-ray crystallography. II. Refinement of yeast hexokinase B co-ordinates and sequence at 2.1 A resolution.
Anderson CM, Stenkamp RE, Steitz TA
J Mol Biol 123 15-33 (1978)
PMID: 355643

Function and Biology Details

Reaction catalysed: 
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138189 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hexokinase-2 Chain: A
Molecule details ›
Chain: A
Length: 457 amino acids
Theoretical weight: 45.85 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P04807 (Residues: 27-471; Coverage: 90%)
Gene names: HEX1, HKB, HXK2, NRB486, YGL253W
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand OTG 1 x OTG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 166.5Å b: 59.2Å c: 58.5Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

Quick links

Citations

9 review citations

Evolution of glycolysis.
Fothergill-Gilmore et al. (1993)
8 more

10 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
9 more