2yps

X-ray diffraction
2.6Å resolution

Crystal structure of the PX domain of human sorting nexin 3

Released:
Source organism: Homo sapiens
Entry authors: Canning P, Kiyani W, Froese DS, Krojer T, Strain-Damerell C, von Delft F, Arrowsmith CH, Edwards AM, Bountra C, Yue WW

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 134 amino acids
Theoretical weight: 15.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60493 (Residues: 24-155; Coverage: 82%)
Gene name: SNX3
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2221
Unit cell:
a: 69.84Å b: 81.7Å c: 184.46Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.211 0.255
Expression system: Escherichia coli BL21(DE3)