› 2yr3

Solution NMR

Solution structure of the fourth Ig-like domain from myosin light chain kinase, smooth muscle

Released:
DOI: 10.2210/pdb2yr3/pdb
PDB entry 2yr3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2yr3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2yr3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Qin XR, Kurosaki C, Yoshida M, Hayahsi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172387 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin light chain kinase, smooth muscle, deglutamylated form Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.46 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15746 (Residues: 510-601; Coverage: 5%)
Gene names: MLCK, MLCK1, MYLK, MYLK1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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