› 2yrs

X-ray diffraction
2.3Å resolution

Human hemoglobin D Los Angeles: crystal structure

Released:
DOI: 10.2210/pdb2yrs/pdb
PDB entry 2yrs coloured by chain, front view.
PDB entry 2yrs coloured by chain, side view.
PDB entry 2yrs coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Poy CD, Moreno F, Bonini-Domingos CR, Filgueira de Azevedo Jr W, Bonilla-Rodriguez GO

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C, I, M
Molecule details ›
Chains: A, C, I, M
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D, K, O
Molecule details ›
Chains: B, D, K, O
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 8 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P21
Unit cell:
a: 82.702Å b: 62.759Å c: 110.216Å
α: 90° β: 90.05° γ: 90°
R-values:
R R work R free
0.165 0.16 0.252

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