› 2ys0

Solution NMR

Solution structure of the Somatomedin B domain of human Ectonucleotide pyrophosphatase/phosphodiesterase family member

Released:
DOI: 10.2210/pdb2ys0/pdb
PDB entry 2ys0 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ys0 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ys0 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Abe H, Sasagawa A, Tochio N, Tomizawa T, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reactions catalysed: 
Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149626 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form Chain: A
Molecule details ›
Chain: A
Length: 56 amino acids
Theoretical weight: 5.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P22413 (Residues: 147-189; Coverage: 5%)
Gene names: ENPP1, M6S1, NPPS, PC1, PDNP1
Sequence domains: Somatomedin B domain
Structure domains: Factor Xa Inhibitor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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