› 2yvq

X-ray diffraction
1.98Å resolution

Crystal structure of MGS domain of carbamoyl-phosphate synthetase from homo sapiens

Released:
DOI: 10.2210/pdb2yvq/pdb
PDB entry 2yvq coloured by chain, front view.
PDB entry 2yvq coloured by chain, side view.
PDB entry 2yvq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Xie Y, Ihsanawati, Kishishita S, Murayama K, Takemoto C, Shirozu M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(1a) ATP + HCO(3)(-) = ADP + carboxyphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-151977 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbamoyl-phosphate synthase [ammonia], mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.61 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P31327 (Residues: 1343-1478; Coverage: 9%)
Gene name: CPS1
Sequence domains: MGS-like domain
Structure domains: Methylglyoxal synthase-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P3221
Unit cell:
a: 50.505Å b: 50.505Å c: 97.634Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.232 0.232 0.279
Expression system: Not provided

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