› 2yxf

X-ray diffraction
1.13Å resolution

The high resolution crystal structure of beta2-microglobulin under physiological conditions

Released:
DOI: 10.2210/pdb2yxf/pdb
PDB entry 2yxf coloured by chain, front view.
PDB entry 2yxf coloured by chain, side view.
PDB entry 2yxf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution crystal structure of beta2-microglobulin formed at pH 7.0.
Iwata K, Matsuura T, Sakurai K, Nakagawa A, Goto Y
J Biochem 142 413-9 (2007)
PMID: 17646174

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158314 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-microglobulin Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: C2
Unit cell:
a: 77.644Å b: 28.907Å c: 54.397Å
α: 90° β: 121.59° γ: 90°
R-values:
R R work R free
0.184 0.184 0.195
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Aggregation of amyloids in a cellular context: modelling and experiment.
Friedman R. (2011)
19 other articles

18 mentions without citation

Rediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases.
Argyropoulos et al. (2017)
17 more