Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157068 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'-AMP-activated protein kinase catalytic subunit alpha-2
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 31.57 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 276 amino acids
Theoretical weight: 31.57 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
- Canonical:
P54646 (Residues: 6-279; Coverage: 50%)
Sequence domains: Protein kinase domain
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL26B2
Spacegroup:
P21
Expression system: Cell-free protein synthesis
