› 2z0n

X-ray diffraction
1.95Å resolution

Crystal structure of APPL1-BAR domain

Released:
DOI: 10.2210/pdb2z0n/pdb
PDB entry 2z0n coloured by chain, front view.
PDB entry 2z0n coloured by chain, side view.
PDB entry 2z0n coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Murayama K, Kato-Murayama M, Sakamoto A, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCC-interacting protein 13-alpha Chain: A
Molecule details ›
Chain: A
Length: 280 amino acids
Theoretical weight: 32.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKG1 (Residues: 1-275; Coverage: 39%)
Gene names: APPL, APPL1, DIP13A, KIAA1428
Sequence domains: BAR domain of APPL family
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44B2
Spacegroup: P21212
Unit cell:
a: 54.121Å b: 128.329Å c: 36.964Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.259
Expression system: Escherichia coli

Quick links