2z4f

Solution NMR

Solution structure of the Discoidin Domain of DDR2

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-172591 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Discoidin domain-containing receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 19.39 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q16832 (Residues: 26-186; Coverage: 19%)
Gene names: DDR2, NTRKR3, TKT, TYRO10
Sequence domains: F5/8 type C domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Komagataella pastoris