2z5m

X-ray diffraction
3Å resolution

Complex of Transportin 1 with TAP NLS, crystal form 2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187824 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transportin-1 Chain: A
Molecule details ›
Chain: A
Length: 890 amino acids
Theoretical weight: 101.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92973 (Residues: 9-898; Coverage: 99%)
Gene names: KPNB2, MIP1, TNPO1, TRN
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Nuclear RNA export factor 1 Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.49 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UBU9 (Residues: 53-82; Coverage: 5%)
Gene names: NXF1, TAP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21212
Unit cell:
a: 132.442Å b: 170.986Å c: 68.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.248 0.267
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided