Function and Biology Details
Reactions catalysed:
(S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O
Citramalyl-CoA = itaconyl-CoA + H(2)O
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
Methylglutaconyl-CoA hydratase, mitochondrial (preferred)
PDBe Complex ID:
PDB-CPX-171822 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methylglutaconyl-CoA hydratase, mitochondrial
Molecule details ›
Chains: A, B, C, D, E, F
Length: 272 amino acids
Theoretical weight: 29.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Enoyl-CoA hydratase/isomerase
Structure domains:
Length: 272 amino acids
Theoretical weight: 29.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q13825 (Residues: 68-339; Coverage: 80%)
Sequence domains: Enoyl-CoA hydratase/isomerase
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL41XU
Spacegroup:
P21
Expression system: Escherichia coli BL21
