› 2aav

Solution NMR

Solution NMR structure of Filamin A domain 17

Released:
DOI: 10.2210/pdb2aav/pdb
PDB entry 2aav coloured by chain, ensemble of 20 models, front view.
PDB entry 2aav coloured by chain, ensemble of 20 models, side view.
PDB entry 2aav coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of the GPIb-filamin A complex.
Nakamura F, Pudas R, Heikkinen O, Permi P, Kilpeläinen I, Munday AD, Hartwig JH, Stossel TP, Ylänne J
Blood 107 1925-32 (2006)
PMID: 16293600

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149204 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-A Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21333 (Residues: 1863-1956; Coverage: 4%)
Gene names: FLN, FLN1, FLNA
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: The structure calculations were made with the program CYANA 2.0 using the automated NOE assignment and structure calculation algorithm. The structure refinement of the 20 final CYANA structures was made with AMBER 8.0 program using the generalized Born continuum solvent model.
Expression system: Escherichia coli

Quick links

Citations

26 review citations

The filamins: organizers of cell structure and function.
Nakamura et al. (2011)
25 more

1 mention without citation

The structure of the GPIb-filamin A complex.
Nakamura et al. (2006)