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SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE

X-ray diffraction
2.5Å resolution
PDB entry 2abl coloured by chain, front view.
PDB entry 2abl coloured by chain, side view.
PDB entry 2abl coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tyrosine-protein kinase ABL1
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Multimeric state: monomeric
Accessible surface area: 9316.2 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132602

Macromolecules

Tyrosine-protein kinase ABL1
Chain: A
Length: 163 amino acids
Theoretical weight: 18.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00519 (Residues: 57-218; Coverage: 14%)
Gene names: ABL, ABL1, JTK7
Pfam:
InterPro:
CATH:
SCOP:
Tyrosine-protein kinase ABL1 in PDB entry 2abl, assembly 1, front view.
Tyrosine-protein kinase ABL1 in PDB entry 2abl, assembly 1, side view.
Tyrosine-protein kinase ABL1 in PDB entry 2abl, assembly 1, top view.
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