› 2ahe

X-ray diffraction
1.8Å resolution

Crystal structure of a soluble form of CLIC4. intercellular chloride ion channel

Released:
DOI: 10.2210/pdb2ahe/pdb
PDB entry 2ahe coloured by chain, front view.
PDB entry 2ahe coloured by chain, side view.
PDB entry 2ahe coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.
Littler DR, Assaad NN, Harrop SJ, Brown LJ, Pankhurst GJ, Luciani P, Aguilar MI, Mazzanti M, Berryman MA, Breit SN, Curmi PM
FEBS J 272 4996-5007 (2005)
PMID: 16176272

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195347 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chloride intracellular channel protein 4 Chain: A
Molecule details ›
Chain: A
Length: 267 amino acids
Theoretical weight: 30.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y696 (Residues: 1-251; Coverage: 99%)
Gene name: CLIC4
Sequence domains: Glutathione S-transferase, N-terminal domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR571
Spacegroup: P21212
Unit cell:
a: 77.717Å b: 79.478Å c: 42.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.229
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Mitochondrial channels: ion fluxes and more.
Szabo et al. (2014)
16 more

11 mentions without citation

The still mysterious roles of cysteine-containing glutathione transferases in plants.
Lallement et al. (2014)
10 more