Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Breakpoint cluster region protein and Afadin (preferred)
PDBe Complex ID:
PDB-CPX-145736 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Afadin
Molecule details ›
Chain: A
Length: 93 amino acids
Theoretical weight: 9.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Length: 93 amino acids
Theoretical weight: 9.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P55196 (Residues: 1003-1094; Coverage: 5%)
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Breakpoint cluster region protein
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 695 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 6 amino acids
Theoretical weight: 695 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P11274 (Residues: 1266-1271; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
