› 2ar6

X-ray diffraction
1.8Å resolution

Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592

Released:
DOI: 10.2210/pdb2ar6/pdb
PDB entry 2ar6 coloured by chain, front view.
PDB entry 2ar6 coloured by chain, side view.
PDB entry 2ar6 coloured by chain, top view.
Source organism: Pterocarpus angolensis
Primary publication:
Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.
Buts L, Garcia-Pino A, Imberty A, Amiot N, Boons GJ, Beeckmans S, Versées W, Wyns L, Loris R
FEBS J 273 2407-20 (2006)
PMID: 16704415

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Legume lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.58 KDa
Source organism: Pterocarpus angolensis
UniProt:
  • Canonical: Q8GSD2 (Residues: 9-260; Coverage: 97%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN, NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: MAN, NAG
Carbohydrate polymer
2 bound ligands:
Ligand MN 2 x MN
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 56.714Å b: 83.592Å c: 122.367Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.201

Quick links

Citations

1 review citation

A survey of the year 2006 literature on applications of isothermal titration calorimetry.
Okhrimenko et al. (2008)
6 other articles

1 mention without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)