› 2avi

X-ray diffraction
3Å resolution

THREE-DIMENSIONAL STRUCTURES OF AVIDIN AND THE AVIDIN-BIOTIN COMPLEX

Released:
DOI: 10.2210/pdb2avi/pdb
PDB entry 2avi coloured by chain, front view.
PDB entry 2avi coloured by chain, side view.
PDB entry 2avi coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Three-dimensional structures of avidin and the avidin-biotin complex.
Livnah O, Bayer EA, Wilchek M, Sussman JL
Proc Natl Acad Sci U S A 90 5076-80 (1993)
PMID: 8506353

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Avidin Chains: A, B
Molecule details ›
Chains: A, B
Length: 128 amino acids
Theoretical weight: 14.35 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P02701 (Residues: 25-152; Coverage: 100%)
Gene name: AVD
Sequence domains: Avidin family
Structure domains: Avidin-like

Ligands and Environments

2 bound ligands:
Ligand NAG 2 x NAG
Ligand BTN 2 x BTN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 72.15Å b: 80.37Å c: 43.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.151 0.151 not available
Expression system: Not provided

Quick links

Citations

27 review citations

Essentials of biorecognition: the (strept)avidin-biotin system as a model for protein-protein and protein-ligand interaction.
Wilchek et al. (2006)
26 more

32 mentions without citation

Antimicrobial Proteins and Peptides in Avian Eggshell: Structural Diversity and Potential Roles in Biomineralization.
Moreau et al. (2022)
31 more