› 2b9z

Solution NMR

Solution structure of FHV B2, a viral suppressor of RNAi

Released:
DOI: 10.2210/pdb2b9z/pdb
PDB entry 2b9z coloured by chain, ensemble of 10 models, front view.
PDB entry 2b9z coloured by chain, ensemble of 10 models, side view.
PDB entry 2b9z coloured by chain, ensemble of 10 models, top view.
Source organism: Flock House virus
Primary publication:
The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Lingel A, Simon B, Izaurralde E, Sattler M
EMBO Rep 6 1149-55 (2005)
PMID: 16270100

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159511 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein B2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 74 amino acids
Theoretical weight: 8.06 KDa
Source organism: Flock House virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68831 (Residues: 1-72; Coverage: 68%)
Gene name: B2
Sequence domains: RNA binding protein B2
Structure domains: ESAT-6-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

25 review citations

RNA-binding proteins: modular design for efficient function.
Lunde et al. (2007)
24 more

5 mentions without citation

The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Lingel et al. (2005)
4 more