Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Protein Tat and Dipeptidyl peptidase 4 (preferred)
PDBe Complex ID:
PDB-CPX-146248 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Dipeptidyl peptidase 4
Molecule details ›
Chains: A, B
Length: 738 amino acids
Theoretical weight: 85.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 738 amino acids
Theoretical weight: 85.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P27487 (Residues: 29-766; Coverage: 96%)
Sequence domains:
Structure domains:
Protein Tat
Molecule details ›
Chains: Y, Z
Length: 9 amino acids
Theoretical weight: 1.03 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
Length: 9 amino acids
Theoretical weight: 1.03 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
- Canonical: P12506 (Residues: 1-9; Coverage: 11%)
Ligands and Environments
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-2
Spacegroup:
P212121
Expression systems:
- Spodoptera frugiperda
- Not provided
