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14-3-3 Protein Theta (Human) Complexed to Peptide

X-ray diffraction
2.8Å resolution
PDB entry 2btp coloured by chain, front view.
PDB entry 2btp coloured by chain, side view.
PDB entry 2btp coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: 14-3-3 protein theta and peptide
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Multimeric state: hetero tetramer
Accessible surface area: 22412.14 Å2
Buried surface area: 3753.88 Å2
Dissociation area: 998.94 Å2
Dissociation energy (ΔGdiss): 5.31 kcal/mol
Dissociation entropy (TΔSdiss): 13.02 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-150976

Macromolecules

14-3-3 protein theta
Chains: A, B
Length: 256 amino acids
Theoretical weight: 29.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P27348 (Residues: 1-234; Coverage: 96%)
Gene name: YWHAQ
Pfam: 14-3-3 protein
InterPro:
CATH: 14-3-3 domain
14-3-3 protein theta in PDB entry 2btp, assembly 1, front view.
14-3-3 protein theta in PDB entry 2btp, assembly 1, side view.
14-3-3 protein theta in PDB entry 2btp, assembly 1, top view.
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CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
Chains: P, Q
Length: 6 amino acids
Theoretical weight: 796 Da
Source organism: Homo sapiens
Expression system: Not provided
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS in PDB entry 2btp, assembly 1, front view.
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS in PDB entry 2btp, assembly 1, side view.
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS in PDB entry 2btp, assembly 1, top view.
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