› 2cbr

X-ray diffraction
2.8Å resolution

CELLULAR RETINOIC ACID BINDING PROTEIN I IN COMPLEX WITH A RETINOBENZOIC ACID (AM80)

Released:
DOI: 10.2210/pdb2cbr/pdb
PDB entry 2cbr coloured by chain, front view.
PDB entry 2cbr coloured by chain, side view.
PDB entry 2cbr coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids.
Chaudhuri BN, Kleywegt GJ, Broutin-L'Hermite I, Bergfors T, Senn H, Le Motte P, Partouche O, Jones TA
Acta Crystallogr D Biol Crystallogr 55 1850-7 (1999)
PMID: 10531482

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular retinoic acid-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 136 amino acids
Theoretical weight: 15.48 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62964 (Residues: 2-137; Coverage: 99%)
Gene name: CRABP1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand A80 1 x A80
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 133.5Å b: 133.5Å c: 40.57Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.23 0.268
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 citation in other articles

"Turn-on" protein fluorescence: in situ formation of cyanine dyes.
Yapici et al. (2015)
5 more

4 mentions without citation

What lessons can be learned from studying the folding of homologous proteins?
Nickson et al. (2010)
3 more