Function and Biology Details
Reaction catalysed:
Hydrolysis of proteins with broad specificity for peptide bonds, but preference for an amino acid bearing a large hydrophobic side chain at the P2 position. Does not accept Val in P1'.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133547 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Papain
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 23.5 KDa
Source organism: Carica papaya
UniProt:
Structure domains: Cysteine proteinases
Length: 212 amino acids
Theoretical weight: 23.5 KDa
Source organism: Carica papaya
UniProt:
- Canonical:
P00784 (Residues: 134-345; Coverage: 65%)
Structure domains: Cysteine proteinases
Proteinase inhibitor I42 chagasin domain-containing protein
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 13.45 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Chagasin family peptidase inhibitor I42
Length: 121 amino acids
Theoretical weight: 13.45 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q868H0 (Residues: 1-121; Coverage: 100%)
Sequence domains: Chagasin family peptidase inhibitor I42
