› 2cqg

Solution NMR

Solution structure of the RNA binding domain of TAR DNA-binding protein-43

Released:
DOI: 10.2210/pdb2cqg/pdb
PDB entry 2cqg coloured by chain, ensemble of 20 models, front view.
PDB entry 2cqg coloured by chain, ensemble of 20 models, side view.
PDB entry 2cqg coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Suzuki S, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171557 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TAR DNA-binding protein 43 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13148 (Residues: 96-185; Coverage: 22%)
Gene names: TARDBP, TDP43
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dyanamics, simulated annealing
Expression system: Not provided

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