› 2cs3

Solution NMR

Solution structure of the zf-C3HC4 domain of human KIAA1865

Released:
DOI: 10.2210/pdb2cs3/pdb
PDB entry 2cs3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2cs3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2cs3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Inoue K, Saitoh K, Hayashi F, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190510 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable E3 ubiquitin-protein ligase IRF2BPL Chain: A
Molecule details ›
Chain: A
Length: 93 amino acids
Theoretical weight: 9.63 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9H1B7 (Residues: 705-784; Coverage: 10%)
Gene names: C14orf4, EAP1, IRF2BPL, KIAA1865, My039
Structure domains: Interferon regulatory factor 2-binding protein

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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