› 2d3r

X-ray diffraction
2.9Å resolution

Cratylia folibunda seed lectin at acidic pH

Released:
DOI: 10.2210/pdb2d3r/pdb
PDB entry 2d3r coloured by chain, front view.
PDB entry 2d3r coloured by chain, side view.
PDB entry 2d3r coloured by chain, top view.
Source organism: Cratylia argentea
Primary publication:
Crystal structures of Cratylia floribunda seed lectin at acidic and basic pHs. Insights into the structural basis of the pH-dependent dimer-tetramer transition.
Del Sol FG, Cavada BS, Calvete JJ
J Struct Biol 158 1-9 (2007)
PMID: 17251039

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160532 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lectin alpha chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 236 amino acids
Theoretical weight: 25.38 KDa
Source organism: Cratylia argentea
UniProt:
  • Canonical: P81517 (Residues: 1-236; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:
Ligand CA 4 x CA
Ligand MN 4 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P212121
Unit cell:
a: 60.213Å b: 125.44Å c: 126.14Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.22

Quick links

Citations

3 review citations

Man-Specific Lectins from Plants, Fungi, Algae and Cyanobacteria, as Potential Blockers for SARS-CoV, MERS-CoV and SARS-CoV-2 (COVID-19) Coronaviruses: Biomedical Perspectives.
Barre et al. (2021)
2 more