› 2dht

X-ray diffraction
2.5Å resolution

Crystal structure of isocitrate dehydrogenase from Sulfolobus tokodaii strain7

Released:
DOI: 10.2210/pdb2dht/pdb
PDB entry 2dht coloured by chain, front view.
PDB entry 2dht coloured by chain, side view.
PDB entry 2dht coloured by chain, top view.
Source organism: Sulfurisphaera tokodaii str. 7
Entry authors: Kondo H, Murakami M, Ihara K, Suzuki S, Kouyama T

Function and Biology Details

Reaction catalysed: 
(1a) isocitrate + NADP(+) = 2-oxalosuccinate + NADPH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188795 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
isocitrate dehydrogenase (NADP(+)) Chains: A, B
Molecule details ›
Chains: A, B
Length: 409 amino acids
Theoretical weight: 46.56 KDa
Source organism: Sulfurisphaera tokodaii str. 7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96YK6 (Residues: 1-409; Coverage: 100%)
Gene names: ST2166, STK_21660, idh
Sequence domains: Isocitrate/isopropylmalate dehydrogenase
Structure domains: Isopropylmalate Dehydrogenase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 73.979Å b: 88.095Å c: 76.216Å
α: 90° β: 91.32° γ: 90°
R-values:
R R work R free
0.241 0.241 0.272
Expression system: Escherichia coli

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