› 2ds7

X-ray diffraction
2.5Å resolution

Structure of the ZBD in the hexagonal crystal form

Released:
DOI: 10.2210/pdb2ds7/pdb
PDB entry 2ds7 coloured by chain, front view.
PDB entry 2ds7 coloured by chain, side view.
PDB entry 2ds7 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structural basis of SspB-tail recognition by the zinc binding domain of ClpX.
Park EY, Lee BG, Hong SB, Kim HW, Jeon H, Song HK
J Mol Biol 367 514-26 (2007)
PMID: 17258768

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141341 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent Clp protease ATP-binding subunit ClpX Chain: A
Molecule details ›
Chain: A
Length: 51 amino acids
Theoretical weight: 5.83 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6H1 (Residues: 2-52; Coverage: 12%)
Gene names: JW0428, b0438, clpX, lopC
Sequence domains: ClpX C4-type zinc finger

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
1 modified residue:
Ligand MSE 1 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P6422
Unit cell:
a: 41.053Å b: 41.053Å c: 102.234Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.239 0.235 0.272
Expression system: Escherichia coli

Quick links

Citations

6 review citations

ClpXP, an ATP-powered unfolding and protein-degradation machine.
Baker et al. (2012)
5 more

3 mentions without citation

Applications of Bacterial Degrons and Degraders - Toward Targeted Protein Degradation in Bacteria.
Izert et al. (2021)
2 more