Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149775 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin-like growth factor-binding protein 4
Molecule details ›
Chain: B
Length: 92 amino acids
Theoretical weight: 9.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Insulin-like growth factor binding protein
Structure domains: Omega-AgatoxinV
Length: 92 amino acids
Theoretical weight: 9.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P22692 (Residues: 22-113; Coverage: 39%)
Sequence domains: Insulin-like growth factor binding protein
Structure domains: Omega-AgatoxinV
Insulin-like growth factor I
Molecule details ›
Chain: I
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9NP10 (Residues: 26-95; Coverage: 67%)
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
