› 2e6k

X-ray diffraction
2.09Å resolution

X-ray structure of Thermus thermopilus HB8 TT0505

Released:
DOI: 10.2210/pdb2e6k/pdb
PDB entry 2e6k coloured by chain, front view.
PDB entry 2e6k coloured by chain, side view.
PDB entry 2e6k coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Yoshida H, Kamitori S, Agari Y, Iino H, Kanagawa M, Nakagawa N, Ebihara A, Kuramitsu S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
transketolase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 651 amino acids
Theoretical weight: 72.68 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SM35 (Residues: 1-651; Coverage: 100%)
Gene name: TTHA0108
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 60 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P1
Unit cell:
a: 72.61Å b: 88.96Å c: 117.18Å
α: 72.48° β: 89.13° γ: 73.36°
R-values:
R R work R free
0.221 0.217 0.259
Expression system: Escherichia coli

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