› 2e73

Solution NMR

Solution structure of the phorbol esters/diacylglycerol binding domain of protein kinase C gamma

Released:
DOI: 10.2210/pdb2e73/pdb
PDB entry 2e73 coloured by chain, ensemble of 20 models, front view.
PDB entry 2e73 coloured by chain, ensemble of 20 models, side view.
PDB entry 2e73 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tanabe W, Suzuki S, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138535 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C gamma type Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.68 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05129 (Residues: 36-105; Coverage: 10%)
Gene names: PKCG, PRKCG
Sequence domains: Phorbol esters/diacylglycerol binding domain (C1 domain)
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Not provided

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