› 2ec6

X-ray diffraction
3.25Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173238 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myosin heavy chain Chain: A
Molecule details ›
Chain: A
Length: 838 amino acids
Theoretical weight: 95.83 KDa
Source organism: Placopecten magellanicus
Expression system: Not provided
UniProt:
  • Canonical: Q26079 (Residues: 1-838; Coverage: 43%)
Sequence domains:
EF-hand domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 133 amino acids
Theoretical weight: 15.35 KDa
Source organism: Placopecten magellanicus
Expression system: Not provided
UniProt:
  • Canonical: Q26069 (Residues: 23-155; Coverage: 82%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
EF-hand domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 156 amino acids
Theoretical weight: 17.62 KDa
Source organism: Placopecten magellanicus
Expression system: Not provided
UniProt:
  • Canonical: Q26066 (Residues: 2-157; Coverage: 99%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 85.273Å b: 50.366Å c: 156.774Å
α: 90° β: 101.04° γ: 90°
R-values:
R R work R free
0.279 0.279 0.3
Expression system: Not provided

Quick links

Citations

9 review citations

Structural and functional insights into the Myosin motor mechanism.
Sweeney et al. (2010)
8 more

3 mentions without citation

Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.
Spudich JA. (2019)
2 more