› 2ecv

Solution NMR

Solution structure of the Zinc finger, C3HC4 type (RING finger) domain of Tripartite motif-containing protein 5

Released:
DOI: 10.2210/pdb2ecv/pdb
PDB entry 2ecv coloured by chain, ensemble of 20 models, front view.
PDB entry 2ecv coloured by chain, ensemble of 20 models, side view.
PDB entry 2ecv coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Abe H, Miyamoto K, Tochio N, Koshiba S, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189886 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tripartite motif-containing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.11 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9C035 (Residues: 1-78; Coverage: 16%)
Gene names: RNF88, TRIM5
Sequence domains: RING-type zinc-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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