› 2ejn

X-ray diffraction
1.64Å resolution

Structural characterization of the tetrameric form of the major cat allergen fel D 1

Released:
DOI: 10.2210/pdb2ejn/pdb
PDB entry 2ejn coloured by chain, front view.
PDB entry 2ejn coloured by chain, side view.
PDB entry 2ejn coloured by chain, top view.
Source organism: Felis catus
Primary publication:
Structural characterization of the tetrameric form of the major cat allergen Fel d 1.
Kaiser L, Velickovic TC, Badia-Martinez D, Adedoyin J, Thunberg S, Hallén D, Berndt K, Grönlund H, Gafvelin G, van Hage M, Achour A
J Mol Biol 370 714-27 (2007)
PMID: 17543334

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151747 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 153 amino acids
Theoretical weight: 17.21 KDa
Source organism: Felis catus
Expression system: Escherichia coli
UniProt:
  • Canonical: P30438 (Residues: 23-92; Coverage: 100%)
  • Canonical: P30440 (Residues: 18-93; Coverage: 83%)
Gene names: CH1, CH2
Sequence domains:
Structure domains: Histone Acetyltransferase; Chain A

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P1
Unit cell:
a: 38.588Å b: 42.996Å c: 48.906Å
α: 70.8° β: 80.56° γ: 81.53°
R-values:
R R work R free
0.19 0.19 0.22
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Animal allergens and their presence in the environment.
Zahradnik et al. (2014)
11 more

15 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
14 more