Function and Biology Details
Reactions catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140146 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein kinase
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.7 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
Length: 14 amino acids
Theoretical weight: 1.7 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
- Canonical:
Q32PK0 (Residues: 314-326; Coverage: 2%)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 12.28 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 105 amino acids
Theoretical weight: 12.28 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P08487 (Residues: 663-759; Coverage: 8%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
