Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141979 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low molecular weight protein-tyrosine-phosphatase Wzb
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.9 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Structure domains: Rossmann fold
Length: 167 amino acids
Theoretical weight: 18.9 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0AAB2 (Residues: 1-147; Coverage: 100%)
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Structure domains: Rossmann fold
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
200 structures were generated in CYANA. The 100 structures with lowest energy were further refined in AMBER7. The 20 lowest energy structures were finally selected.
Expression system: Escherichia coli BL21(DE3)
