Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158945 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitogen-activated protein kinase 1
Molecule details ›
Chains: A, B
Length: 364 amino acids
Theoretical weight: 42.16 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 364 amino acids
Theoretical weight: 42.16 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P63086 (Residues: 2-358; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Dual specificity protein phosphatase 6
Molecule details ›
Chains: C, D
Length: 17 amino acids
Theoretical weight: 1.94 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
Length: 17 amino acids
Theoretical weight: 1.94 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
- Canonical: Q64346 (Residues: 60-76; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU300
Spacegroup:
P21
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
