› 2g31

Solution NMR

Human Nogo-A functional domain: nogo60

Released:
DOI: 10.2210/pdb2g31/pdb
PDB entry 2g31 coloured by chain, ensemble of 20 models, front view.
PDB entry 2g31 coloured by chain, ensemble of 20 models, side view.
PDB entry 2g31 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Nogo goes in the pure water: solution structure of Nogo-60 and design of the structured and buffer-soluble Nogo-54 for enhancing CNS regeneration.
Li M, Liu J, Song J
Protein Sci 15 1835-41 (2006)
PMID: 16877707

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Reticulon-4 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9NQC3 (Residues: 1055-1114; Coverage: 5%)
Gene names: KIAA0886, My043, NOGO, RTN4, SP1507
Sequence domains: Reticulon
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

The reticulons: a family of proteins with diverse functions.
Yang et al. (2007)
3 more

2 mentions without citation

Resurrecting abandoned proteins with pure water: CD and NMR studies of protein fragments solubilized in salt-free water.
Li et al. (2006)
1 more