› 2gao

X-ray diffraction
2Å resolution

Crystal Structure of Human SAR1a in Complex With GDP

Released:
DOI: 10.2210/pdb2gao/pdb
PDB entry 2gao coloured by chain, front view.
PDB entry 2gao coloured by chain, side view.
PDB entry 2gao coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang J, Dimov S, Tempel W, Yaniw D, Arrowsmith C, Edwards A, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192536 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small COPII coat GTPase SAR1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 208 amino acids
Theoretical weight: 23.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NR31 (Residues: 10-198; Coverage: 96%)
Gene names: SAR1, SAR1A, SARA, SARA1
Sequence domains: ADP-ribosylation factor family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 2 x GDP
Ligand UNX 2 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 57.295Å b: 63.814Å c: 62.132Å
α: 90° β: 105.94° γ: 90°
R-values:
R R work R free
0.226 0.224 0.269
Expression system: Escherichia coli

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