› 2gbp

X-ray diffraction
1.9Å resolution

SUGAR AND SIGNAL-TRANSDUCER BINDING SITES OF THE ESCHERICHIA COLI GALACTOSE CHEMORECEPTOR PROTEIN

Released:
DOI: 10.2210/pdb2gbp/pdb
PDB entry 2gbp coloured by chain, front view.
PDB entry 2gbp coloured by chain, side view.
PDB entry 2gbp coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Sugar and signal-transducer binding sites of the Escherichia coli galactose chemoreceptor protein.
Vyas NK, Vyas MN, Quiocho FA
Science 242 1290-5 (1988)
PMID: 3057628

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142447 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-galactose/methyl-galactoside binding periplasmic protein MglB Chain: A
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 33.41 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0AEE5 (Residues: 24-332; Coverage: 100%)
Gene names: JW2137, b2150, mglB
Sequence domains: Periplasmic binding protein domain
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
Ligand BGC 1 x BGC
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 66Å b: 37.05Å c: 61.57Å
α: 90° β: 106.8° γ: 90°
R-values:
R R work R free
0.146 not available not available
Expression system: Not provided

Quick links

Citations

12 review citations

Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes.
Quiocho et al. (1996)
11 more

29 mentions without citation

The role of solute binding proteins in signal transduction.
Matilla et al. (2021)
28 more