› 2ggo

X-ray diffraction
1.8Å resolution

Crystal Structure of glucose-1-phosphate thymidylyltransferase from Sulfolobus tokodaii

Released:
DOI: 10.2210/pdb2ggo/pdb
PDB entry 2ggo coloured by chain, front view.
PDB entry 2ggo coloured by chain, side view.
PDB entry 2ggo coloured by chain, top view.
Source organism: Sulfurisphaera tokodaii
Entry authors: Rajakannan V, Mizushima T, Suzuki A, Masui R, Kuramitsu S, Yamane T

Function and Biology Details

Reactions catalysed: 
Acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + N-acetyl-alpha-D-glucosamine 1-phosphate
Acetyl-CoA + alpha-D-galactosamine 1-phosphate = CoA + N-acetyl-alpha-D-galactosamine 1-phosphate
UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-alpha-D-glucosamine
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose
UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-alpha-D-galactosamine
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-188842 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 44.57 KDa
Source organism: Sulfurisphaera tokodaii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q975F9 (Residues: 1-401; Coverage: 100%)
Gene names: ST0452, STK_04520
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: R3
Unit cell:
a: 122.999Å b: 122.999Å c: 94.884Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.222 0.267
Expression system: Escherichia coli

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