2go5

Electron Microscopy
7.4Å resolution

Structure of signal recognition particle receptor (SR) in complex with signal recognition particle (SRP) and ribosome nascent chain complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-131344 (preferred)
Entry contents:
7 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (9 distinct):
Signal recognition particle 19 kDa protein Chain: B
Molecule details ›
Chain: B
Length: 108 amino acids
Theoretical weight: 12.56 KDa
Source organism: Canis sp.
Expression system: Not provided
UniProt:
  • Canonical: Q5RBR1 (Residues: 14-120; Coverage: 74%)
Gene name: SRP19
Sequence domains: SRP19 protein
Signal recognition particle subunit SRP54 Chain: W
Molecule details ›
Chain: W
Length: 109 amino acids
Theoretical weight: 12.47 KDa
Source organism: Canis sp.
Expression system: Not provided
UniProt:
  • Canonical: P61010 (Residues: 326-434; Coverage: 22%)
Gene name: SRP54
Sequence domains: Signal peptide binding domain
Signal recognition particle receptor subunit alpha Chain: 1
Molecule details ›
Chain: 1
Length: 185 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P08240 (Residues: 3-176; Coverage: 27%)
Gene names: SRPR, SRPRA
Sequence domains: Signal recognition particle, alpha subunit, N-terminal
Signal recognition particle receptor subunit beta Chain: 2
Molecule details ›
Chain: 2
Length: 214 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P47758 (Residues: 58-269; Coverage: 79%)
Gene name: Srprb
Sequence domains: Signal recognition particle receptor beta subunit
Large ribosomal subunit protein uL29 Chain: 5
Molecule details ›
Chain: 5
Length: 124 amino acids
Theoretical weight: 14.4 KDa
Source organism: Triticum sp.
Expression system: Not provided
UniProt:
  • Canonical: Q8L805 (Residues: 1-124; Coverage: 100%)
Gene name: RPL35
Sequence domains: Ribosomal L29 protein
Ribosomal protein L25 Chain: 4
Molecule details ›
Chain: 4
Length: 152 amino acids
Theoretical weight: 16.92 KDa
Source organism: Triticum sp.
Expression system: Not provided
UniProt:
  • Canonical: O81229 (Residues: 1-109; Coverage: 100%)
Sequence domains: Ribosomal protein L23
Putative 60S ribosomal protein L31 Chain: 6
Molecule details ›
Chain: 6
Length: 123 amino acids
Theoretical weight: 14.15 KDa
Source organism: Triticum sp.
Expression system: Not provided
UniProt:
  • Canonical: Q5XLD9 (Residues: 1-124; Coverage: 99%)
Sequence domains: Ribosomal protein L31e
SRP RNA Chain: A
Molecule details ›
Chain: A
Length: 127 nucleotides
Theoretical weight: 41.2 KDa
Sequence domains: Metazoan signal recognition particle RNA
ribosomal RNA Chain: 9
Molecule details ›
Chain: 9
Length: 90 nucleotides
Theoretical weight: 29.17 KDa
Sequence domains: Archaeal large subunit ribosomal RNA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.4Å
Relevant EMDB volumes: EMD-1217
Expression system: Not provided