Function and Biology Details
Sequence domains:
- p53 tumour suppressor family
- p53, DNA-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- p53-like transcription factor, DNA-binding domain superfamily
- p53/RUNT-type transcription factor, DNA-binding domain superfamily
- Helicase, superfamily 3, DNA virus
- Zinc finger, large T-antigen D1-type
- Large T antigen, polyomavirus, C-terminal
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
Large T antigen and Cellular tumor antigen p53 (preferred)
PDBe Complex ID:
PDB-CPX-136541 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Large T antigen
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 370 amino acids
Theoretical weight: 42.65 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli
UniProt:
Structure domains:
Length: 370 amino acids
Theoretical weight: 42.65 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli
UniProt:
- Canonical:
P03070 (Residues: 260-627; Coverage: 52%)
Structure domains:
Cellular tumor antigen p53
Molecule details ›
Chains: M, N, O, P, Q, R, S, T, U, V, W, X
Length: 203 amino acids
Theoretical weight: 22.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
Length: 203 amino acids
Theoretical weight: 22.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P04637 (Residues: 92-292; Coverage: 51%)
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like
