› 2h4r

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130725 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heterochromatin-associated protein MENT Chain: A
Molecule details ›
Chain: A
Length: 415 amino acids
Theoretical weight: 48.03 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O73790 (Residues: 1-410; Coverage: 100%)
Gene names: MENT, SERPINB10
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 46.203Å b: 74.022Å c: 57.505Å
α: 90° β: 95.42° γ: 90°
R-values:
R R work R free
0.209 0.205 0.282
Expression system: Escherichia coli BL21

Quick links

Citations

10 review citations

Conformational pathology of the serpins: themes, variations, and therapeutic strategies.
Gooptu et al. (2009)
9 more

5 mentions without citation

X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
McGowan et al. (2006)
4 more