› 2hcu

X-ray diffraction
2.1Å resolution

Crystal Structure Of Smu.1381 (or LeuD) from Streptococcus Mutans

Released:
DOI: 10.2210/pdb2hcu/pdb
PDB entry 2hcu coloured by chain, front view.
PDB entry 2hcu coloured by chain, side view.
PDB entry 2hcu coloured by chain, top view.
Source organism: Streptococcus mutans
Entry authors: Gao ZQ, Hou HF, Li LF, Liang YH, Su XD, Dong YH

Function and Biology Details

Reaction catalysed: 
(1a) (2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184202 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-isopropylmalate dehydratase small subunit Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 24.38 KDa
Source organism: Streptococcus mutans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8DTG5 (Residues: 1-196; Coverage: 100%)
Gene names: SMU_1381, leuD
Sequence domains: Aconitase C-terminal domain
Structure domains: Aconitase, domain 4

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P65
Unit cell:
a: 74.033Å b: 74.033Å c: 82.519Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.188 0.218
Expression system: Escherichia coli BL21(DE3)

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