› 2heh

X-ray diffraction
2.15Å resolution

Crystal Structure of the KIF2C motor domain

Released:
DOI: 10.2210/pdb2heh/pdb
PDB entry 2heh coloured by chain, front view.
PDB entry 2heh coloured by chain, side view.
PDB entry 2heh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang J, Shen Y, Tempel W, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189238 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF2C Chain: A
Molecule details ›
Chain: A
Length: 387 amino acids
Theoretical weight: 43.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99661 (Residues: 225-593; Coverage: 51%)
Gene names: KIF2C, KNSL6
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
Ligand UNX 10 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P43212
Unit cell:
a: 79.72Å b: 79.72Å c: 154.885Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.22 0.254
Expression system: Escherichia coli

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